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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Passive immune transfer (PIT) and dynamics of specific antibodies in calves naturally exposed to the respiratory viruses

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Author(s):
B.T. Silva [1] ; C.C. Baccili [2] ; A. Henklein [3] ; P.L. Oliveira [4] ; S.M.F.N. Oliveira [5] ; N.M. Sobreira [6] ; C.P. Ribeiro [7] ; V. Gomes [8]
Total Authors: 8
Affiliation:
[1] Universidade de São Paulo - Brasil
[2] Universidade de São Paulo - Brasil
[3] Universidade de São Paulo - Brasil
[4] Universidade de São Paulo - Brasil
[5] Universidade de São Paulo - Brasil
[6] Universidade de São Paulo - Brasil
[7] Instituto Biológico - Brasil
[8] Universidade de São Paulo - Brasil
Total Affiliations: 8
Document type: Journal article
Source: Arquivo Brasileiro de Medicina Veterinária e Zootecnia; v. 70, n. 5, p. 1414-1422, 2018-10-00.
Abstract

ABSTRACT This research evaluated the PIT and the dynamics of specific antibody (Ab) for calves naturally exposed to the viral agents involved in Bovine Respiratory Disease (BRD). Nineteen Holstein calves fed colostrum from vaccinated donors for DRB. Serum samples were obtained before and after colostrum intake (48h) for serum neutralization (SN). Mean values (log2) detected after colostrum feeding were 11.5±1.6 (BVDV), 8.8 ±1.3 (BoHV-1) 5.5±1.6 (BRSV) and 8.4±1.5 (BPIV-3). Five calves were raised from birth to 240 days of life and presented a decrease in Ab titers for BVDV, BoHV-1 and BPIV-3 over time (P≤ 0.001). Infection rates from D14 to D240 were of 40% (2/5), 20% (1/5), 80% (4/5) and 60% (3/5), respectively for BVDV, BoHV-1, BRSV and BPIV-3. Most of the calves presented bronchopneumonia after seroconversion to the virus. Calves presented Ab for all viruses at 48 hours of life, however BRSV Ab titer were low. Levels and persistence of maternal antibody titers determined the susceptibility to viral infections. (AU)

FAPESP's process: 12/02129-8 - Developmente of specific immune response in calves and its influence on response to vaccine bovine viral diarrhea virus
Grantee:Viviani Gomes
Support Opportunities: Regular Research Grants