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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Computed tomography of mast cell tumors in dogs: assessment before and after chemotherapy

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Author(s):
Carla A.B. Lorigados [1] ; Julia Maria Matera [2] ; Antonio A. Coppi [3] ; Thaís R. Macedo [4] ; Fernando V.L. Ladd [5] ; Vanessa A.F. de Souza ; Ana Carolina B.C.F. Pinto [7]
Total Authors: 7
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Cirurgia - Brasil
[2] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Cirurgia - Brasil
[3] USP. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Cirurgia
[4] USP. FMVZ. Departamento de Cirurgia
[5] USP. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Cirurgia
[7] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Cirurgia - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Pesquisa Veterinária Brasileira; v. 33, n. 11, p. 1349-1356, 2013-11-00.
Abstract

Nineteen dogs with mast cell tumors treated with chemotherapy were evaluated by computed tomography (CT). Were evaluated aspects related to contours, attenuation, post-contrast enhancement and presence of cleavage with adjacent structures. The RECIST criteria and volumetric measurement of lesions were performed to assess the response to treatment. The mast cell tumors presented a homogeneous or heterogeneous attenuation, presented more frequently a well delineated and regular contours and moderate enhancement after intravenous administration of the iodinated contrast media. The methods RECIST and volumetric measurements showed an excellent agreement to the classification of therapeutic response, providing a good parameter of the response to treatment. The CT examination proved to be useful in the delimitation of the tumor and an important tool for planning of surgical margins. (AU)

FAPESP's process: 09/02359-0 - Comparison of protocol efficacy of Imatinib Mesylate versus Vimblastina with Prednison on the treatment of canine mast cell tumors - clinical - surgical - histhopathologycal - imunohysthochemical and molecular study
Grantee:Julia Maria Matera
Support Opportunities: Regular Research Grants