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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Post operative pain: analgesic combinations and adverse effects

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Author(s):
Silvia Regina Secoli [1] ; Vanessa Cristina Moraes [2] ; Aparecida de Cássia Giani Peniche [3] ; Maria de Fátima Fernandes Vattimo [4] ; Yeda Aparecida de Oliveira Duarte [5] ; Isabel Yovana Quispe Mendoza [6]
Total Authors: 6
Affiliation:
[1] Universidade de São Paulo. Escola de Enfermagem. Departamento de Enfermagem Médico Cirúrgica - Brasil
[2] Universidade de São Paulo. Escola de Enfermagem - Brasil
[3] Universidade de São Paulo. Escola de Enfermagem. Departamento de Enfermagem Médico Cirúrgica - Brasil
[4] Universidade de São Paulo. Escola de Enfermagem. Departamento de Enfermagem Médico Cirúrgica - Brasil
[5] Universidade de São Paulo. Escola de Enfermagem. Departamento de Enfermagem Médico Cirúrgica - Brasil
[6] Universidade de São Paulo. Escola de Enfermagem - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Revista da Escola de Enfermagem da USP; v. 43, p. 1244-1249, 2009-12-00.
Abstract

The control f the pains and its adverse affects are in the focus of health professionals and institutional managers in order to optimize clinical outcomes. The objectives of this study were to analyze the prevalence of medicine combination and interaction and to verify the association of this with the observed adverse effects. It was a descriptive, exploratory and retrospective study. The sample was composed by 260 patient data submitted to hemorrhoidectomy, up to 60 years old, healthy. Results showed that the mostly used medicine associations were dipyrone sodium and omeprazole (33.7%), dypirone sodium and ketoprofen (23.6%) and cetoprofen and lactulose (22.8%). It was observed that ketoprofen + omeprazole (p=0.001) and ketoprofen + lactulose (p=0.03) were significantly associated with bleeding. It was observed that, excepting ketoprofen, the other medicine association identified in the study showed to be safe to be used in the post surgical period. (AU)