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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Use of molybdenum rich mineral mix in the prevention of cumulative cooper poisoning in sheep - hepatic microminerals

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Author(s):
A.C. Antonelli [1] ; R.A. Barrêto Júnior [2] ; C.S. Mori [3] ; A.H.H. Minervino [4] ; U.M. Schalch [5] ; J.C.G. Pacheco [6] ; E.L. Ortolani [7]
Total Authors: 7
Affiliation:
[1] Universidade Federal do Vale do São Francisco - Brasil
[2] Universidade Federal Rural do Semi-Árido - Brasil
[3] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[4] Universidade Federal do Oeste do Pará - Brasil
[5] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[6] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[7] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Arquivo Brasileiro de Medicina Veterinária e Zootecnia; v. 68, n. 3, p. 629-635, 2016-06-00.
Abstract

ABSTRACT The aim of this project is to evaluate the capacity of a molybdenum-rich mineral salt in the prevention of cumulative cooper poisoning (CCP) in sheep, through clinical and hepatic copper and molybdenum concentrations. Twenty five crossbreed Ile-de-France sheep were randomly distributed equally into five groups. Group 1 received a 80% forage and 20% concentrate diet, groups 2 and 3 received a 50% forage and 50% concentrate diet, and groups 4 and 5 received the same diet as groups 2 and 3 with a daily supplementation of 150 mg of copper sulfate. Groups 1, 3 and 5 received a mineral salt with 300 ppm of molybdenum. Three times during the experiment a liver biopsy was carried out to evaluate the degree of copper accumulation. Three sheep from group 4 and one sheep from group 5 showed a clinical picture of CCP. There was no difference in the frequency of mortality between groups 4 and 5 (P=0.56). The liver copper concentration was higher in sheep with CCP (2450 ppm) compared to sheep that did not present CCP (1518 ppm). The higher the ingestion of molybdenum in the diet the lower the liver copper concentration at the end of the experiment (r=-0.72). (AU)

FAPESP's process: 05/02291-6 - Evaluation of a mineral mix with high levels of molybdenum in the prevention of accumulative copper poisoning in sheep
Grantee:Enrico Lippi Ortolani
Support Opportunities: Regular Research Grants