| Full text | |
| Author(s): |
Luciana Neder
[1]
;
Marlon van Weelden
;
Gabriela Ribeiro Viola
[3]
;
Daniela Mencaroni Lourenço
[4]
;
Claudio A. Len
[5]
;
Clovis A. Silva
Total Authors: 6
|
| Affiliation: | [1] Universidade Federal do Mato Grosso (UFMT). Serviço de Dermatologia - Brasil
[3] Universidade de São Paulo. Faculdade de Medicina. Unidade de Reumatologia Pediátrica - Brasil
[4] Universidade de São Paulo. Faculdade de Medicina. Unidade de Reumatologia Pediátrica - Brasil
[5] Universidade Federal de São Paulo. Unidade de Reumatologia Pediátrica - Brasil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | REVISTA BRASILEIRA DE REUMATOLOGIA; v. 55, n. 5, p. 414-419, 2015-10-00. |
| Abstract | |
ABSTRACTObjective:To evaluate the health-related quality of life (HRQL) in pediatric leprosy patients.Methods:A cross-secal study included 47 leprosy patients and 45 healthy subjects. The HRQL was measured by Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0), and evaluated physical, emotional, social and school domains. The leprosy patients were classified by Ridley and Jopling classification criteria and assessed according to clinical musculoskeletal manifestations, laboratory and radiographic examinations.Results:The median of current age was similar in leprosy patients and controls [12 (6-18) vs. 15 (5-18) years, p = 0.384], likewise the frequencies of female gender (p = 0.835) and middle/lower Brazilian socio-economic classes (p = 1.0). The domain school activities according the child-self report was significantly lower in leprosy patients compared to controls in the age group of 13-18 years [75 (45-100) vs. 90 (45-100), p = 0.021]. The other domains were alike in both groups (p > 0.05). At least one musculoskeletal manifestation (arthralgia, arthritis and/or myalgia) was observed in 15% of leprosy patients and none in controls (p= 0.012). Further comparison between all leprosy patients showed that the median of the physical capacity domain [81.25 (50-100) vs. 98.44 (50-100), p = 0.036] and school activities domain by child-self report [60 (50-85) vs. 80 (45-100), p = 0.042] were significantly lower in patients with musculoskeletal manifestations compared to patients without these manifestations. No differences were evidenced between the other HRQL parameters in both groups, reported by patients and parents (p > 0.05).Conclusions:Reduced physical capacity and school activities domains were observed in pediatric leprosy patients with musculoskeletal manifestations. (AU) | |
| FAPESP's process: | 08/58238-4 - Autoimmunity in children: investigation of the molecular and cellular bases of early onset of autoimmunity |
| Grantee: | Magda Maria Sales Carneiro-Sampaio |
| Support Opportunities: | Research Projects - Thematic Grants |