Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Multilocus enzyme electrophoresis typing of Candida albicans populations isolated from healthy children according to socioeconomic background

Full text
Author(s):
Marcelo Fabiano Gomes Boriollo [1] ; Edvaldo Antônio Ribeiro Rosa [2] ; Wagner Luis de Carvalho Bernardo [3] ; Denise Madalena Palomari Spolidorio [4] ; Reginaldo Bruno Gonçalves [5] ; José Francisco Höfling [6]
Total Authors: 6
Affiliation:
[1] State University of Campinas. Dental School of Piracicaba. Microbiology and Immunology Laboratory - Brasil
[2] Pontifical Catholic University of Paraná. Center of Biological and Health Sciences
[3] State University of Campinas. Dental School of Piracicaba. Microbiology and Immunology Laboratory - Brasil
[4] Paulista State University. School of Dentistry. Department of Physiology and Pathology - Brasil
[5] State University of Campinas. Dental School of Piracicaba. Microbiology and Immunology Laboratory - Brasil
[6] State University of Campinas. Dental School of Piracicaba. Microbiology and Immunology Laboratory - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Revista Brasileira de Epidemiologia; v. 8, n. 1, p. 51-66, 2005-03-00.
Abstract

The aim of this research was to evaluate the genetic diversity within and between C. albicans populations isolated from the oral cavity of healthy Brazilian children classified into five socioeconomic categories (A to E). Multilocus Enzyme Electrophoresis (MLEE) analysis was the method used to assess genetic diversity. High genetic diversity was observed in all populations that showed predominance of some C. albicans subtypes (Electrophoretic Types - ETs). However, no correlation was observed between a specific ET and a specific population of children. Clustering analysis showed one or more highly related ET clusters, suggesting the existence of indirect and direct propagation routes of C. albicans among healthy children. Microevolutionary changes were observed in some C. albicans populations isolated from children with the same or very similar socioeconomic condition. Furthermore, low transition of C. albicans subtypes can be occurring among certain populations of children coming from high and medium/high, or high and medium/low, or medium/high and medium/low socioeconomic categories, which can also be explained by their own socioeconomic and cultural characteristics. (AU)