| Full text | |
| Author(s): |
Balfour, Michael N.
[1]
;
Zukerman-Schpector, Julio
[2]
;
Davila Rodriguez, Maria Jose
[2]
;
Reis, Joel Savi
[1]
;
Esteves, Carlos Henrique A.
[1]
;
Stefani, Helio A.
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Dept Farm, Fac Ciencias Farmaceut, Ave Prof Lineu Prestes 580, Sao Paulo, SP - Brazil
[2] Univ Fed Sao Carlos, Dept Quim, Lab Cristalog Estereodinam & Modelagem Mol, Sao Carlos, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Synthetic Communications; v. 49, n. 3, p. 351-358, FEB 1 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
The synthesis of a library of 2,6-disubstituted-azaindoles relying on Sonogashira cross-coupling and intramolecular cyclization is described. Eleven examples of 6-alkynyl derivatives and three examples of 3-bromo-5-azaindoles are reported. One of the 3-bromo-5-azaindoles was also further functionalized with two different aryl trifluoroborate salts via Suzuki-Miyaura coupling reaction. {[}GRAPHICS] . (AU) | |
| FAPESP's process: | 14/19221-0 - Synthesis of libraries for use in biological testing of Chagas Disease |
| Grantee: | Michael Nils Balfour |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 16/02392-1 - 2-Aryloxazolines: Synthesis, Biological Activity and Fluorescence |
| Grantee: | Joel Savi dos Reis |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/26673-2 - CuH-Catalyzed fluorination of alkenes and PET applications |
| Grantee: | Carlos Henrique Alves Esteves |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/24821-4 - Carbonylative Coupling and Intramolecular Cycloaddition [2 + 2] Reactions Employing D-Glucal |
| Grantee: | Helio Alexandre Stefani |
| Support Opportunities: | Regular Research Grants |