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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effects of diode laser setting for laryngeal surgery in a rabbit model

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Author(s):
Arroyo-Ramos, Helena Hotz [1] ; Neri, Larissa [1] ; Mancini, Marilia Wellichan [2] ; Duarte Neto, Amaro Nunes [3] ; Mauad, Thais [3] ; Imamura, Rui [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Dept Otolaryngol, Sch Med, Av Dr Eneas Carvalho Aguiar, 255-6 Andar Aala 6167, BR-05403000 Sao Paulo, SP - Brazil
[2] Res & Educ Ctr Phototherapy Hlth Sci NUPEN, Sao Carlos, SP - Brazil
[3] Univ Sao Paulo, Dept Pathol, Sch Med, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY; v. 276, n. 5, p. 1431-1438, MAY 2019.
Web of Science Citations: 0
Abstract

Purpose To study the damaging effect of different diode laser settings on vocal folds 7 days after injury in a rabbit model. Methods Twenty-one male New Zealand white rabbits were randomized into three groups with seven animals per group. A 980-nm diode laser was used to create a single spot injury in each vocal fold. Different modulation frequencies (10 Hz versus 1000 Hz) in pulsed mode, different powers (3 W versus 5 W), and distinct wave modes of radiation (pulsed versus continuous) were compared. Results The extent of the inflammatory infiltrate and ablation crater were greater when using 5-W optical power compared with 3 W. The extent and depth of the inflammatory infiltrate, and the width and depth of the ablation crater were greater with continuous wave mode compared with pulsed mode. The density of collagen fibers only increased when using the laser in continuous wave mode. Conclusion The use of the 980-nm diode laser with an output power of 5 W produced an increased extent of thermal injury compared to an output power of 3 W and, more importantly, using continuous rather than pulsed wave mode significantly increased the extent and depth of thermal injury in rabbit vocal folds. (AU)

FAPESP's process: 15/25095-0 - Study of vocal fold healing with 980 nm wavelength diode laser in a rabbit model
Grantee:Rui Imamura
Support Opportunities: Regular Research Grants