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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Syndromes related to sodium and arginine vasopressin alterations in post-operative neurosurgery

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Author(s):
Ana P.D. Cardoso [1] ; Desanka Dragosavac [2] ; Sebastião Araújo [3] ; Antonio L.E. Falcão [4] ; Renato G.G. Terzi [5] ; Margaret de Castro [6] ; Fabiana G. Marcondes [7] ; Taís G. Melo [8] ; Rosmari A.R.A. Oliveira [9] ; Eliana A. Cintra [10]
Total Authors: 10
Affiliation:
[1] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[2] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[3] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[4] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[5] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[6] University of São Paulo. Faculty of Medicine of Ribeirão Preto. Department of Clinical Pathology - Brasil
[7] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[8] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[9] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
[10] State University of Campinas. School of Medical Sciences. Department of Surgery - Brasil
Total Affiliations: 10
Document type: Journal article
Source: Arquivos de Neuro-Psiquiatria; v. 65, p. 745-751, 2007-09-00.
Abstract

BACKGROUND: Cerebral salt wasting syndrome (CSWS), syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diabetes insipidus (DI) are frequently found in postoperative neurosurgery. PURPOSE: To identify these syndromes following neurosurgery. METHOD: The study included 30 patients who had been submitted to tumor resection and cerebral aneurysm clipping. Sodium levels in serum and urine and urine volume were measured daily up to the 5th day following surgery. Plasma arginine vasopressin (AVP) was measured on the first, third and fifth days post-surgery. RESULTS: CSWS was found in 27/30 patients (90%), in 14 (46.7%) of whom it was associated with a reduction in the levels of plasma AVP (mix syndrome). SIADH was found in 3/30 patients (10%). There was no difference between the two groups of patients. CONCLUSION: CSWS was the most common syndrome found, and in half the cases it was associated with DI. SIADH was the least frequent syndrome found. (AU)