Juvenile hormone signaling in insect oogenesis

Author(s)

Santos, Carolina Goncalves ^[1] ; Humann, Fernanda Carvalho ^[2] ; Hartfelder, Klaus ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Biol Celular & Mol & Bioagentes Patogen, Ribeirao Preto, SP - Brazil

^[2] Inst Fed Sao Paulo, Campus Matao, Matao, SP - Brazil

• Document type: Review article
• Source: CURRENT OPINION IN INSECT SCIENCE; v. 31, p. 43-48, FEB 2019.
• Web of Science Citations: 10

Abstract

Juvenile hormone (JH) plays a crucial role in insect reproduction, but its molecular mode of action only became clear within the last decade. We here review recent findings revealing the intricate crosstalk between JH and ecdysone signaling with nutrient sensing pathways in Drosophila melanogaster, Aedes aegypti, Tribolium castaneum and Locusta migratoria. The finding for a critical role of ecdysis triggering hormone (ETH) in both molting and ooogenesis now also highlights the importance of an integrated view of development and reproduction. Furthermore, insights from non-model insects, especially so social Hymenoptera and termites, where JH function gradually becomes decoupled from reproduction and plays a role in division of labor, emphasize the need to consider life cycle and life history strategies when studying insect reproductive physiology. (AU)

• FAPESP's process: 17/09128-0 - Molecular basis of the disruption in the reproduction-longevity trade-off syndrome in the social insect model organism Apis mellifera
• Grantee: Klaus Hartmann Hartfelder
• Support Opportunities: Regular Research Grants