Knee crepitus is not associated with the occurrence of total knee replacement in knee osteoarthritis - a longitudinal study with data from the Osteoarthritis Initiative

Author(s)

Pazzinatto, Marcella Ferraz ^{[1, 2]} ; Silva, Danilo de Oliveira ^{[1, 2]} ; de Azevedo, Fabio Micolis ^[1] ; Pappas, Evangelos ^[3]

Affiliation

^[1] Univ Estadual Paulista, Sch Sci & Technol, Phys Therapy Dept, UNESP, Presidente Prudente, SP - Brazil

^[2] La Trobe Univ, La Trobe Sports & Exercise Med Res Ctr LASEM, Sch Allied Hlth, Bundoora, Vic - Australia

^[3] Univ Sydney, Fac Hlth Sci, Discipline Physiotherapy, Sydney, NSW - Australia

• Document type: Journal article
• Source: BRAZILIAN JOURNAL OF PHYSICAL THERAPY; v. 23, n. 4, p. 329-336, JUL-AUG 2019.
• Web of Science Citations: 1

Abstract

Objective(s): To investigate whether the presence of knee crepitus is associated with the occurrence of total knee replacement (TKR), quality of life and deficits in physical function at long-term. Methods: Setting - This observational study uses longitudinal data (up to 4-year follow-up) from the Osteoarthritis Initiative (OAI). Participants - 4566 participants. Main Outcome Measure(s) - Logistic regression models were used to test if baseline knee crepitus is associated with the occurrence of TKR. Linear mixed models with adjustment for confounding variables (age, gender, BMI and Kellgren-Lawrence grade) were used to test the association between baseline knee crepitus and longitudinal changes in the pain, self-reported physical function, quality of life and performance-based function. Results: The presence of knee crepitus at baseline does not predict the occurrence of TKR at 36 months (p = 0.58 and 0.67 for right and left knees, respectively). The crepitus group presented a slightly knee extension strength decline from baseline to 48 months (p= 0.03 for the right and 0.01 for the left knee; between group difference =2% for both right {[}95%CI = -0.12; -0.01] and left knees {[}95%CI = -0.13; -0.02]). Conclusion: The presence of knee crepitus is not associated with the occurrence of TKR in the following three years. Knee crepitus is associated with slightly declines in knee extension strength, but this does not seem to affect physical function and quality of life at long-term. (C) 2018 Associacao Brasileira de Pesquisa e Pos-Graduacao em Fisioterapia. Published by Elsevier Editora Ltda. All rights reserved. (AU)

• FAPESP's process: 15/10631-3 - Does it matter that my knee clicks? a longitudinal study of functional decline based on the presence of CREPITUS: data from the osteoarthritis initiative
• Grantee: Marcella Ferraz Pazzinatto
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• FAPESP's process: 15/11534-1 - INFLUENCE OF PAIN IN THE ANALYSIS OF PROXIMAL, LOCAL AND DISTAL KINEMATIC PARAMETERS IN FEMALES WITH PATELLOFEMORAL PAIN DURING STAIR ASCENT AND DESCENT
• Grantee: Danilo de Oliveira Silva
• Support Opportunities: Scholarships in Brazil - Doctorate