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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Heart defibrillation: relationship between pacing threshold and defibrillation probability

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Author(s):
Antoneli, Priscila C. [1] ; Goulart, Jair T. [2] ; Bonilha, Isabella [3] ; de Carvalho, Daniela D. [3] ; de Oliveira, Pedro X. [1, 4]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, UNICAMP, Sch Elect & Comp Engn FEEC, Dept Biomed Engn, Rua Alexander Fleming 163, Cidade Univ Zeferino, BR-13083881 Campinas, SP - Brazil
[2] Univ Brasilia UnB, Inst Biol, Dept Physiol Sci, Campus Univ Darcy Ribeiro, BR-70910900 Brasilia, DF - Brazil
[3] Univ Estadual Campinas, UNICAMP, Fac Med Sci, Lab Myocardial Ischemia Reperfus, Rua Cinco Junho 350, Bloco 1, Cidade Univ Zeferino, BR-13083877 Campinas, SP - Brazil
[4] Univ Estadual Campinas, UNICAMP, Ctr Biomed Engn, Rua Alexander Fleming 163, Cidade Univ Zeferino, BR-13083881 Campinas, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: BIOMEDICAL ENGINEERING ONLINE; v. 18, n. 1 SEP 13 2019.
Web of Science Citations: 0
Abstract

Background Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation parameters to increase its efficiency. In this study, we investigated the influence of stimuli duration on the relationship between pacing threshold and defibrillation probability. Results We found out that 0.5-ms-long pulses had a lower ratio of defibrillation probability to the pacing threshold, although the higher the pulse duration the lower is the electric field intensity required to defibrillate the hearts. Conclusion The appropriate choice of defibrillatory shock parameters is able to increase the efficiency of the defibrillation improving the survival chances after the occurrence of a severe arrhythmia. The relationship between pulse duration and the probability of reversal of fibrillation shows that this parameter cannot be underestimated in defibrillator design since different pulse durations have different levels of safety. (AU)