A metal-free approach to access ketones, amides, and nitriles employing TBAI/TBHP oxidative system in water

Gomes, Suzane Quintana; Salles, Jr., Airton G.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A metal-free approach to access ketones, amides, and nitriles employing TBAI/TBHP oxidative system in water

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Author(s):	Gomes, Suzane Quintana ^[1] ; Salles, Jr., Airton G. ^[1] Total Authors: 2
Affiliation:	^[1] Univ Estadual Campinas, Inst Chem, Dept Organ Chem, Monteiro Lobato St, POB 6154, BR-13084862 Campinas, SP - Brazil Total Affiliations: 1
Document type:	Journal article
Source:	Synthetic Communications; v. 49, n. 23, p. 3389-3399, DEC 2 2019.
Web of Science Citations:	0
Abstract
Hydrocarbons, benzylamines, and heteroaromatic-bearing amines have been efficiently employed as substrates in allylic and benzylic oxidations via C(sp3)?H bond activation by TBAI/TBHP in water. This operationally simple method allows access to ketones, nitriles, and amides in moderate to high yields and a regio- and chemoselective late-stage functionalization. (AU)

FAPESP's process:	17/18400-6 - Tandem allylic/benzylic oxidation-Michael addition/aldol reaction using TBAI as a single catalyst: An expedient protocol to increase structural complexity.
Grantee:	Airton Goncalves Salles Junior
Support Opportunities:	Regular Research Grants

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