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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation A protocol for an interventional study

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Author(s):
Padilha Rego, Rebeca Mayara [1] ; Machado, Nilton Carlos [2] ; Carvalho, Mary de Assis [2] ; Graffunder, Johann Souza [1] ; Paiva Ortolan, Erika Veruska [3] ; Toledo de Arruda Lourencao, Pedro Luiz [3]
Total Authors: 6
Affiliation:
[1] UNESP Sao Paulo State Univ, Botucatu Med Sch, Botucatu, SP - Brazil
[2] UNESP Sao Paulo State Univ, Botucatu Med Sch, Dept Pediat, Pediat Gastroenterol Hepatol & Nutr Div, Botucatu, SP - Brazil
[3] UNESP Sao Paulo State Univ, Botucatu Med Sch, Dept Surg & Orthoped, Div Pediat Surg, Botucatu, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: MEDICINE; v. 98, n. 45 NOV 2019.
Web of Science Citations: 0
Abstract

Introduction: A vast majority of children with functional constipation respond to the standard medical treatment. However, a subset of patients may present with an unsatisfactory response and only minor improvement of symptoms. Transcutaneous posterior tibial nerve stimulation (PTNS) involves electrical stimulation of the posterior tibial nerve at the level of the ankle, transcutaneously through electrodes fixated on the overlying skin. Stimulation of the tibial nerve can modulate urinary and defecatory function through the stimulation of sacral nerves. Thus, transcutaneous PTNS can be considered a very promising, noninvasive, and safe method to be used in the pediatric age group. However, there is still no published study that has investigated its use in children for the treatment of intestinal constipation. This is a single-center, prospective, longitudinal, and interventional study designed to assess the applicability and clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation. Children will be submitted to daily sessions of transcutaneous PTNS for a period of 4 weeks. All children will also be invited to participate in semistructured interviews, 1 in each of the 3 assessments: 1 week before the start of the intervention; immediately after the 4 weeks of intervention; and 4 weeks after the end of the intervention period. In these interviews, the aspects related to bowel habits and quality of life will be assessed. This project aims to evaluate the clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation and the applicability of this kind of treatment. Conclusions: This protocol intended to demonstrate the efficacy of this promising method to increase the number of bowel movements and the stool consistency, to reduce the number of episodes of retentive fecal incontinence, and to indirectly improve the overall quality of life. (AU)

FAPESP's process: 19/08361-9 - Evaluation of the initial impact of transcutaneous posterior tibial nerve stimulation in children with intestinal constipation
Grantee:Johann Souza Graffunder
Support Opportunities: Scholarships in Brazil - Scientific Initiation