Comparison between Plasma Electrolytic Oxidation Coating and Sandblasted Acid-Etched Surface Treatment: Histometric, Tomographic, and Expression Levels of Osteoclastogenic Factors in Osteoporotic Rats

Author(s)

Correia Momesso, Gustavo Antonio ^[1] ; de Souza Santos, Anderson Maikon ^[1] ; Fonseca e Santos, Joao Matheus ^[1] ; da Cruz, Nilson Cristino ^[2] ; Okamoto, Roberta ^[3] ; Ricardo Barao, Valentim Adelino ^[4] ; Siroma, Rafael Shinoske ^[5] ; Shibli, Jamil Awad ^[5] ; Faverani, Leonardo Perez ^[1]

Affiliation

^[1] Sao Paulo State Univ Unesp, Aracatuba Sch Dent, Dept Diag & Surgery, Sao Paulo 16015050 - Brazil

^[2] Sao Paulo State Univ Unesp, Technol Plasma Lab LaPTec, Expt Campus Sorocaba, Sorocaba 18087180 - Brazil

^[3] Sao Paulo State Univ Unesp, Aracatuba Sch Dent, Dept Basic Sci, Sao Paulo 16018800 - Brazil

^[4] Univ Campinas Unicamp, Piracicaba Sch Dent, Dept Prosthodont & Periodontol, Sao Paulo 13414903 - Brazil

^[5] Univ Guarulhos UnG, Dept Periodontol & Oral Implantol, Dent Res Div, Guarulhos 07115230, SP - Brazil

• Document type: Journal article
• Source: MATERIALS; v. 13, n. 7 APR 2020.
• Web of Science Citations: 0

Abstract

Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats. (AU)

• FAPESP's process: 16/20297-6 - The influence of commercially pure Titanium (cpTi) coating with Ca and P incorporation produced by plasma electrolytic oxidation on low density bone: An in vitro, ex-vivo and in vivo study
• Grantee: Leonardo Perez Faverani
• Support Opportunities: Regular Research Grants