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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Screen-printed disposable electrodes using graphite-polyurethane composites modified with magnetite and chitosan-coated magnetite nanoparticles for voltammetric epinephrine sensing: a comparative study

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Author(s):
Mattioli, Isabela A. [1] ; Cervini, Priscila [1] ; Cavalheiro, Eder T. G. [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Inst Quim Sao Carlos, Av Trabalhador Sao Carlense 400, BR-13566590 Sao Carlos, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Microchimica Acta; v. 187, n. 6 MAY 10 2020.
Web of Science Citations: 0
Abstract

Disposable screen-printed electrodes based on the use of graphite-polyurethane composites modified with magnetite nanoparticles (MNP-SPE) or chitosan-coated magnetite nanoparticles (CHMNP-SPE) are described. The MNP and CHMNP were synthetized and comparatively characterized by TEM, XRD, FTIR, and TGA/DTG. The MNP-SPE and CHMNP-SPE were characterized by SEM and EDX. After optimization of the MNP percentage in MNP-SPE, the materials were electrochemically characterized by cyclic voltammetry, EIS, and chronocoulometry. The electrodes were tested for their performance towards sensing of epinephrine (EP). The CHMNP-SPE is found to have better electrochemical responses in comparison to the MNP-SPE. This is assumed to be due to the chitosan coating which also protects the MNPs from oxidation under air and at different applied potential fields. The performances of the MNP-SPE and CHMNP-SPE were studied by DPV after optimization of equilibration time and DPV parameters. Response is linear in the 0.1-0.8 mu M EP concentration range, at 0.03 V (vs. pseudo-Ag/AgCl), and the detection limit is 25 nM for the MNP-SPE. The linear response for the CHMNP-SPE was 0.1-0.6 mu M, at 0.0 V (vs. pseudo-Ag/AgCl), and a LOD of 14 nM was achieved. The devices were used for the quantification of EP in synthetic urine and in cerebrospinal synthetic fluids. Recoveries from spiked samples are in the 95.6-102.2% range for the CHMNP-SPE and in the 98.3-109% range for MNP-SPE. The stability of the respective sensors was investigated and compared over a period of 5 months. The EP peak currents were found to decrease by only 4% for the CHMNP-SPE, while the MNP-SPE lost 23% of its EP peak current. Accordingly, the CHMNP-SPE was chosen as the most stable and sensitive sensor for EP. (AU)

FAPESP's process: 18/11071-0 - Development and application of disposable screen-printed composite electrodes based on metallic nanoparticles and graphite-polyurethane
Grantee:Isabela Alteia Mattioli
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 17/04211-7 - Development of inks based on metalic nanoparticles and polymers for the preparation of conventional and printed electrodes
Grantee:Éder Tadeu Gomes Cavalheiro
Support Opportunities: Regular Research Grants