Photodynamic therapy in combination with surgery for the treatment of an extensive squamous cell carcinoma in situ - A case report

Author(s)

Salvio, Ana Gabriela ^[1] ; Stringasci, Mirian Denise ^[2] ; Requena, Michelle Barreto ^[2] ; Bagnato, Vanderlei Salvador ^{[3, 2, 4]}

Affiliation

^[1] Amaral Carvalho Canc Hosp, Skin Dept, Jau, SP - Brazil

^[2] Univ Sao Paulo, Sao Carlos Inst Phys, Sao Paulo - Brazil

^[3] Texas A&M Univ, College Stn, TX - USA

^[4] Texas A&M Univ, College Stn, TX USA.Salvio, Ana Gabriela, Amaral Carvalho Canc Hosp, Skin Dept, Jau, SP - Brazil

• Document type: Journal article
• Source: Photodiagnosis and Photodynamic Therapy; v. 30, JUN 2020.
• Web of Science Citations: 1

Abstract

The combination of multiple sessions of Photodynamic therapy (PDT) and surgery have been used to treat an extensive superficial lesion of squamous cell carcinoma in situ. Methyl aminolevulinate (MAL) mediated PDT was applied to reduce the tumoral area and a small surgical removal was performed to complete elimination of the lesion. The reduction of the tumor area avoided the need for a skin graft application as well as possible postoperative complications, offering a more favorable cosmetic outcome. Two-years of follow-up showed no recurrence. The case is interesting and demonstrate potentialities for the combined use of PDT and surgery. (AU)

• FAPESP's process: 14/50857-8 - National Institute in Basic Optics and Applied to Life Sciences
• Grantee: Vanderlei Salvador Bagnato
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 13/07276-1 - CEPOF - Optics and Photonic Research Center
• Grantee: Vanderlei Salvador Bagnato
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC