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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Intermittent explosive disorder subtypes in the general population: association with comorbidity, impairment and suicidality

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Author(s):
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Scott, K. M. [1] ; de Vries, Y. A. [2, 3] ; Aguilar-Gaxiola, S. [4] ; Al-Hamzawi, A. [5] ; Alonso, J. [6, 7, 8] ; Bromet, E. J. [9] ; Bunting, B. [10] ; Caldas-de-Almeida, J. M. [11, 12] ; Cia, A. [13] ; Florescu, S. [14] ; Gureje, O. [15] ; Hu, C-Y [16, 17] ; Karam, E. G. [18, 19, 20] ; Karam, A. [19] ; Kawakami, N. [21] ; Kessler, R. C. [22] ; Lee, S. [23] ; McGrath, J. [24, 25, 26] ; Oladeji, B. [27, 28] ; Posada-Villa, J. [29] ; Stein, D. J. [30, 31, 32] ; Zarkov, Z. [33, 34] ; de Jonge, P. [2, 3] ; Collabor, World Mental Hlth Surveys
Total Authors: 24
Affiliation:
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[1] Univ Otago, Dunedin Sch Med, Dept Psychol Med, POB 56, Dunedin 9054 - New Zealand
[2] Univ Med Ctr Groningen, Interdisciplinary Ctr Psychopathol & Emot Regulat, Dept Psychiat, Groningen - Netherlands
[3] Univ Groningen, Dept Dev Psychol, Groningen - Netherlands
[4] UC Davis Hlth Syst, Ctr Reducing Hlth Dispar, Sacramento, CA - USA
[5] Al Qadisiya Univ, Coll Med, Diwaniya Governorate - Iraq
[6] Pompeu Fabra Univ UPF, Barcelona - Spain
[7] CIBER Epidemiol & Salud Publ CIBERESP, Barcelona - Spain
[8] IMIM Hosp del Mar, Heaith Serv Res Unit, Med Res Inst, Barcelona - Spain
[9] SUNY Stony Brook, Dept Psychiat, Sch Med, Stony Brook, NY 11794 - USA
[10] Ulster Univ, Sch Psychol, Coleraine, Londonderry - North Ireland
[11] Univ Nova Lisboa, Fac Ciencias Med, Lisbon Inst Global Mental Hlth, NOVA Med Sch, Lisbon - Portugal
[12] Univ Nova Lisboa, Fac Ciencias Med, Chron Dis Res Ctr CEDOC, NOVA Med Sch, Lisbon - Portugal
[13] Anxiety Disorders Ctr, Buenos Aires, DF - Argentina
[14] Natl Sch Publ Hlth Management & Dev, Bucharest - Romania
[15] Univ Coll Hosp, Dept Psychiat, Ibadan - Nigeria
[16] Shenzhen Inst Mental Hlth, Shenzhen - Peoples R China
[17] Shenzhen Kangning Hosp, Shenzhen - Peoples R China
[18] Balamand Univ, Fac Med, Dept Psychiat & Clin Psychol, Beirut - Lebanon
[19] Inst Dev Res Advocacy & Appl Care IDRAAC, Beirut - Lebanon
[20] St George Hosp Univ, Dept Psychiat & Clin Psychol, Med Ctr, Beirut - Lebanon
[21] Univ Tokyo, Sch Publ Hlth, Dept Mental Hlth, Tokyo - Japan
[22] Harvard Med Sch, Dept Hlth Care Policy, Boston, MA 02115 - USA
[23] Chinese Univ Hong Kong, Dept Psychiat, Tai Po, Hong Kong - Peoples R China
[24] Queensland Ctr Mental Hlth Res, Pk Ctr Mental Hlth, Wacol, Qld 4072 - Australia
[25] Univ Queensland, Queensland Brain Inst, St Lucia, Qld 4065 - Australia
[26] Aarhus Univ, Natl Ctr Register Based Res, DK-8000 Aarhus V - Denmark
[27] Univ Coll Hosp, Ibadan - Nigeria
[28] Univ Ibadan, Coll Med, Dept Psychiat, Ibadan - Nigeria
[29] Colegio Mayor Cundinamarca Univ, Fac Social Sci, Bogota - Colombia
[30] Groote Schuur Hosp, Cape Town - South Africa
[31] Univ Cape Town, Dept Psychiat & Mental Hlth, Res Unit Risk & Resilience Mental Disorders, Cape Town - South Africa
[32] Univ Cape Town, South African Med Council, Res Unit Risk & Resilience Mental Disorders, Cape Town - South Africa
[33] Natl Ctr Publ Hlth & Anal, Dept Mental Hlth, Sofia - Bulgaria
[34] Natl Ctr Publ Hlth & Anal, Dept Mental Hlth, Sofia, Bulgaria.Scott, K. M., Univ Otago, Dunedin Sch Med, Dept Psychol Med, POB 56, Dunedin 9054 - New Zealand
Total Affiliations: 34
Document type: Journal article
Source: EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES; v. 29, 2020.
Web of Science Citations: 0
Abstract

Aims Intermittent explosive disorder (IED) is characterised by impulsive anger attacks that vary greatly across individuals in severity and consequence. Understanding IED subtypes has been limited by lack of large, general population datasets including assessment of IED. Using the 17-country World Mental Health surveys dataset, this study examined whether behavioural subtypes of IED are associated with differing patterns of comorbidity, suicidality and functional impairment. Methods IED was assessed using the Composite International Diagnostic Interview in the World Mental Health surveys (n= 45 266). Five behavioural subtypes were created based on type of anger attack. Logistic regression assessed association of these subtypes with lifetime comorbidity, lifetime suicidality and 12-month functional impairment. Results The lifetime prevalence of IED in all countries was 0.8% (s.e.: 0.0). The two subtypes involving anger attacks that harmed people ('hurt people only' and `destroy property and hurt people'), collectively comprising 73% of those with IED, were characterised by high rates of externalising comorbid disorders. The remaining three subtypes involving anger attacks that destroyed property only, destroyed property and threatened people, and threatened people only, were characterised by higher rates of internalising than externalising comorbid disorders. Suicidal behaviour did not vary across the five behavioural subtypes but was higher among those with (v. those without) comorbid disorders, and among those who perpetrated more violent assaults. Conclusions The most common IED behavioural subtypes in these general population samples are associated with high rates of externalising disorders. This contrasts with the findings from clinical studies of IED, which observe a preponderance of internalising disorder comorbidity. This disparity in findings across population and clinical studies, together with the marked heterogeneity that characterises the diagnostic entity of IED, suggests that it is a disorder that requires much greater research. (AU)

FAPESP's process: 03/00204-3 - Epidemiological study of psychiatric disorders in the São Paulo Metropolitan Region: prevalence, risk factors, and social and economical burden
Grantee:Laura Helena Silveira Guerra de Andrade
Support Opportunities: Research Projects - Thematic Grants