Predictors of severe pain during insertion of the levonorgestrel 52 mg intrauterine system among nulligravid women

Author(s)

Ferreira, Leticia Sanchez ^[1] ; de Nadai, Mariane Nunes ^[1] ; Poli-Neto, Omero B. ^[1] ; Franceschini, Silvio A. ^[1] ; Juliato, Cassia R. T. ^[2] ; Monteiro, Ilza Maria U. ^[2] ; Bahamondes, Luis ^[2] ; Vieira, Carolina Sales ^[1]

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Obstet & Gynecol, Ave Bandeirantes 3900, Campus Univ Monte Alegre, BR-14049900 Ribeirao Preto, SP - Brazil

^[2] Univ Estadual Campinas, Fac Med Sci, Dept Obstet & Gynecol, Caixa Postal 6181, BR-13084971 Campinas, SP - Brazil

• Document type: Journal article
• Source: Contraception; v. 102, n. 4, p. 267-269, OCT 2020.
• Web of Science Citations: 0

Abstract

Objective: To identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women. Study design: We performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed factors associated with severe pain (visual analog scale pain score >= 7) immediately after insertion using bivariate and multiple regression analyses. Results: Overall, 137/300 (45.7%) subjects reported severe pain. In multiple regression analysis, only intracervical anesthesia {[}RR 0.55, 95% CI 0.37-0.80] and a history of dysmenorrhea {[}RR 1.36, 95% CI 1.08-1.72)] were associated with severe pain. Conclusions: Among nulligravid women, a history of dysmenorrhea increases, and intracervical block decreases severe pain during levonorgestrel IUS insertion. (C) 2020 Elsevier Inc. All rights reserved. (AU)

• FAPESP's process: 17/12938-4 - Effect of intracervical anesthesia on pain associated with the insertion of the levonorgestrel-releasing intrauterine system in nulliparous women: a randomized clinical trial
• Grantee: Omero Benedicto Poli Netto
• Support Opportunities: Regular Research Grants