Comparison Between Treacher Collins Syndrome and Pierre Robin Sequence: A Cephalometric Study

Author(s)

Kato, Renata Mayumi ^[1] ; Moura, Priscila Padilha ^[2] ; Zechi-Ceide, Roseli Maria ^[2] ; Tonello, Cristiano ^[3] ; Peixoto, Adriano Porto ^[4] ; Garib, Daniela ^{[5, 4]}

Affiliation

^[1] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Bauru, SP - Brazil

^[2] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Dept Genet, Bauru, SP - Brazil

^[3] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Hosp Dept, Bauru, SP - Brazil

^[4] Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Dept Orthodont, Bauru, SP - Brazil

^[5] Univ Sao Paulo, Bauru Dent Sch, Bauru, SP - Brazil

• Document type: Journal article
• Source: CLEFT PALATE-CRANIOFACIAL JOURNAL; v. 58, n. 1, p. 78-83, JAN 2021.
• Web of Science Citations: 0

Abstract

Objective: The aim of this study was to compare the dentoskeletal pattern of Treacher Collins syndrome (TCS) and nonsyndromic Pierre Robin sequence (PRS). Design: Retrospective. Setting: Single center. Patients: Eighteen patients diagnosed with TCS (Group TCS) or PRS (Group PRS) in rehabilitation treatment at a single center. Group TCS was composed of 9 patients (4 male, 5 female) with a mean age of 12.9 years (standard deviation = 4.8). Group PRS was composed of 9 patients paired by age and sex with group TCS. Main Outcome Measure(s): Cone beam computed tomography-derived cephalometric images taken before the orthodontic or the orthodontic-surgical treatment were analyzed using Dolphin Imaging (Dolphin Imaging 11.0 \& Management Solutions). Variables evaluating the cranial base, the maxillary and mandibular skeletal components, maxillomandibular relationship, the vertical components and the dentoalveolar region were measured. Intergroup comparisons were performed using t tests. The significance level considered was 5%. Results: Intergroup differences in the mandible size and growth pattern were observed. Group TCS showed a smaller mandibular length (Co-Go, Co-Gn) and a higher palatal plane (SN-Palatal Plane) and mandibular plane angles (SN-Go.Gn) compared to group PRS. No differences between TCS and PRS were observed for the sagittal position of the maxilla, maxillomandibular relationship, and dental components. Conclusions: Treacher Collins syndrome presented a decreased mandible and a more severe vertical growth pattern compared to PRS. (AU)

• FAPESP's process: 18/00061-3 - Mandibular characterization of individuals with isolated Robin sequence and Treacher Collins syndrome: three-dimensional evaluation
• Grantee: Renata Mayumi Kato
• Support Opportunities: Scholarships in Brazil - Master