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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Carbohydrate and Glutamine Supplementation Attenuates the Increase in Rating of Perceived Exertion during Intense Exercise in Hypoxia Similar to 4200 m

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Author(s):
Caris, V, Aline ; Thomatieli-Santos, V, Ronaldo
Total Authors: 2
Document type: Journal article
Source: NUTRIENTS; v. 12, n. 12 DEC 2020.
Web of Science Citations: 0
Abstract

The rating of perceived exertion (RPE) indicates the feeling of fatigue. However, hypoxia worsens the condition and can worsen RPE. We evaluated whether carbohydrate and glutamine supplementation alters RPE and physiological markers in running at 70% peak oxygen uptake until exhaustion in a simulated altitude of 4500 m. Nine volunteers underwent three running tests at 70% peak oxygen uptake until exhaustion: (1) hypoxia and placebo, (2) hypoxia and 8% maltodextrin, and (3) hypoxia after six days of glutamine supplementation (20 g/day) and 8% maltodextrin. The exercise and supplementation were randomized and double-blinded. Lactate, heart rate, haemoglobin O-2 saturation (SpO(2)%), and RPE (6-20 scale) were analyzed at the 15th and 30th min. The level of significance was set at p <= 0.05. SpO(2)% decreased at the 15th and 30th minutes compared to resting in placebo, carbohydrate, and glutamine supplementation. RPE increased at the 30th minute compared to the 15th minute in placebo and carbohydrate supplementation; however, there was no difference in the glutamine supplementation condition. Heart rate and lactate increased after the 15th and 30th minutes compared to resting, similar to the three conditions studied. We conclude that previous supplementation with glutamine and carbohydrate during intense exercise in hypoxia similar to 4500 m can attenuate the increase in RPE by the increase in glycemia and can be a useful strategy for people who exercise in these conditions. (AU)

FAPESP's process: 17/26563-2 - Effects of carbohydrate and glutamine supplementation on parameters of innate immune response and inflammation during and after exercise in hypoxia
Grantee:Ronaldo Vagner Thomatieli dos Santos
Support Opportunities: Regular Research Grants