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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Protective Effect of Solutions Containing Polymers Associated with Fluoride and Stannous Chloride on Hydroxyapatite Dissolution

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Augusto, Marina Gullo [1] ; Santos, Tamires Maria de Andrade [1] ; Scaramucci, Tais [2] ; Aoki, Idalina Vieira [3] ; Torres, Carlos Rocha Gomes [1] ; Hara, Anderson Takeo [4] ; Borges, Alessandra Buhler [1]
Total Authors: 7
[1] Sao Paulo State Univ, Inst Sci & Technol, Dept Restorat Dent, UNESP, Sao Jose Dos Campos - Brazil
[2] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Sao Paulo - Brazil
[3] Univ Sao Paulo, Dept Chem Engn, Polytech Sch, Sao Paulo - Brazil
[4] Indiana Univ, Sch Dent, Dept Cariol Operat Dent & Dent Publ Hlth, Indianapolis, IN - USA
Total Affiliations: 4
Document type: Journal article
Source: Caries Research; v. 55, n. 2 JAN 2021.
Web of Science Citations: 0

This study investigated the protective effect of experimental solutions containing 4 polymers (polyoxirane, hydroxypropylmethylcellulose {[}HPMC], pectin, and an amino methacrylate copolymer {[}AMC]) in 2 concentrations (low and high) associated or not with sodium fluoride (F; 225 ppm F-) or sodium fluoride plus stannous chloride (FS; 800 ppm Sn2+) on the dissolution of hydroxyapatite crystals (HA). Deionized water was the control. The pretreated HA was added to a 0.3% citric acid solution (pH 3.8). An automatic titrant machine added aliquots of 0.1 N HCl at a rate of 28 mu L/min, in a total reaction time of 5 min. Groups were compared with 2-way ANOVA and Tukey's test, and concentrations with Student t test (5%). The zeta potential of the HA treated with the solutions was measured. Significant differences were found for both factors and interaction (p < 0.0001). The treatments with F and FS solutions resulted in a lower amount of dissolved HA than the control. Among the polymers' solutions, only AMC was able to reduce the amount of dissolved HA, changing the surface charge of HA to positive. AMC improved the protective effect of F, but it did not affect FS. Polyoxirane and HPMC reduced the protective potential of the FS solution. No differences were found between the concentrations of the polymers. It was concluded that F and FS reduced the amount of dissolved HA. The protective effect of the experimental solutions against HA dissolution was polymer dependent. The F effect was enhanced by its combination with AMC, but the protection of FS was impaired by polyoxirane and HPMC. (AU)

FAPESP's process: 16/15755-5 - Anti-erosive effect of solutions containing different polymers
Grantee:Marina Gullo Augusto
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 17/13799-8 - Antierosive potential of fluoridated solutions associated or not to film-forming polymers
Grantee:Alessandra Buhler Borges
Support Opportunities: Regular Research Grants