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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil

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Author(s):
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Márcio Junio Lima Siconelli ; Daniel Macedo de Melo Jorge ; Luiza Antunes de Castro-Jorge ; Antônio Augusto Fonseca-Júnior ; Mateus Laguardia Nascimento ; Vitor Gonçalves Floriano ; Fransérgio Rocha de Souza ; Eudson Maia de Queiroz-Júnior ; Marcelo Fernandes Camargos ; Eliana Dea Lara Costa ; Adolorata Aparecida Bianco Carvalho ; Benedito Antonio Lopes da Fonseca
Total Authors: 12
Document type: Journal article
Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 54, p. -, 2021.
Web of Science Citations: 0
Abstract

Abstract INTRODUCTION: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. AIM: We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019. METHODS: WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq. RESULTS: Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. CONCLUSIONS: Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years. (AU)

FAPESP's process: 20/01632-4 - Evaluation of the circulation of West Nile Virus in the State of São Paulo: birds and equines as a sentinel population
Grantee:Márcio Junio Lima Siconelli
Support type: Scholarships in Brazil - Doctorate