Frontal Hemodynamic Response During Step Initiation Under Cognitive Conflict in Older and Young Healthy People

Author(s)

Coelho, Daniel Boari ^[1] ; Bazan, Paulo Rodrigo ^{[2, 3]} ; Zimeo Morais, Guilherme Augusto ^[3] ; Balardin, Joana Bisol ^[3] ; Batista, Alana Xavier ^[2] ; Neves de Oliveira, Claudia Eunice ^[1] ; Los Angeles, Emanuele ^[1] ; Bernardo, Claudionor ^[1] ; Sato, Joao Ricardo ^[4] ; de Lima-Pardini, Andrea C. ^[5]

Affiliation

^[1] Fed Univ ABC, Biomed Engn, Sao Bernardo Do Campo, SP - Brazil

^[2] Univ Sao Paulo, Fac Med, Dept Radiol, Sao Paulo - Brazil

^[3] Hosp Israelita Albert Einstein, Big Data Analyt, Sao Paulo - Brazil

^[4] Univ Fed ABC, Ctr Math Comp & Cognit, Sao Bernardo Do Campo, SP - Brazil

^[5] Queens Univ, Ctr Neurosci Studies, Lab Integrat Motor Behav, Kingston, ON - Canada

• Document type: Journal article
• Source: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES; v. 76, n. 2, p. 216-223, FEB 2021.
• Web of Science Citations: 0

Abstract

Gait initiation is a daily challenge even for healthy individuals as it requires the timely coupling between the automatic anticipatory postural adjustment (APA) and the voluntary step according to the context. Modulation of this motor event has been thought to involve higher level brain control, including cognitive inhibitory circuitries. Despite the known participation of the supplementary motor area (SMA) in the modulation of some parameters of APA, the participation of areas controlling inhibition during gait initiation still needs to be investigated. In this study, the hemodynamic responses of the SMA and dorsolateral prefrontal cortex (DLPFC) were assessed using functional near-infrared spectroscopy (fNIRS) during a gait initiation task under cognitive conflict to select the foot to step (congruent {[}CON] and incongruent {[}INC] conditions). The older group (OG) showed worse inhibitory control than the young group (YG) along with more impairments in APA parameters. OG also had a lower amplitude of hemodynamic responses in both areas than YG in the INC. The INC increased the correlation between SMA and DLPFC only in the YG. Aging seems to impair the interaction between the hemodynamic responses of SMA and DLPFC, which influences APA performance in gait initiation under cognitive conflict. (AU)

• FAPESP's process: 15/14810-0 - Biomechanical and functional aspects of the musculoskeletal system of runners: chronic effects of therapeutic exercise and aging
• Grantee: Isabel de Camargo Neves Sacco
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/06604-1 - Biomechanical modelling and clinical assessment data gathering with technological innovations towards movement restoration and sports performance for people with disabilities
• Grantee: Claudiane Arakaki Fukuchi
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 14/13502-7 - Effect of the velocity of locomotion in gait movement pattern of young adults and elderly individuals: experimental study, computational simulation and creation of public database
• Grantee: Claudiane Arakaki Fukuchi
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)