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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Omics Tools Applied to the Study of Chagas Disease Vectors: Cytogenomics and Genomics

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Author(s):
Borsatto, Kelly Cristine [1] ; Coronado, Monika Aparecida [1] ; Arni, Raghuvir Krishnaswamy [1] ; Chaboli Alevi, Kaio Cesar [2]
Total Authors: 4
Affiliation:
[1] Univ Estadual Paulista, Ctr Multiusuario Inovacao Biomol, Inst Biociencias Letras & Ciencias Exatas, Dept Fis, UNESP, Rua Cristavao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto - Brazil
[2] Univ Estadual Paulista, Fac Ciencias Farmaceut, Dept Ciencias Biol, Lab Parasitol, UNESP, Araraquara, SP - Brazil
Total Affiliations: 2
Document type: Review article
Source: American Journal of Tropical Medicine and Hygiene; v. 104, n. 6, p. 1973-1977, JUN 2021.
Web of Science Citations: 0
Abstract

Chagas disease is an illness caused by the protozoan Trypanosoma cruzi that is distributed in 21 countries of Latin America. The main way of transmission of T. cruzi is through the feces of triatomines infected with the parasite. With technological advances came new technologies called omics. In the pre-genomic era, the omics science was based on cytogenomic studies of triatomines. With the Rhodnius prolixus genome sequencing project, new omics tools were applied to understand the organism at a systemic level and not just from a genomic point of view. Thus, the present review aims to put together the cytogenomic and genomic information available in the literature for Chagas disease vectors. Here, we review all studies related to cytogenomics and genomics of Chagas disease vectors, contributing to the direction of further research with these insect vectors, because it was evident that most studies focus on cytogenomic knowledge of the species. Given the importance of genomic studies, which contributed to the knowledge of taxonomy, systematics, as well as the vector's biology, the need to apply these techniques in other genera and species of Triatominae subfamily is emphasized. (AU)

FAPESP's process: 18/25458-3 - Analysis of parasite-vector interaction of Chagas Disease metabolic profile
Grantee:Kelly Cristine Borsatto
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)