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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control

Full text
Author(s):
Garibaldi, Pedro M. M. [1] ; Ferreira, Natasha N. [1] ; Moraes, Glenda R. [2] ; Moura, Jose C. [3] ; Esposito, Danillo L. A. [4] ; Volpe, Gustavo J. [1] ; Calado, Rodrigo T. [5] ; Fonseca, Benedito A. L. [4] ; Borges, Marcos C. [4]
Total Authors: 9
Affiliation:
[1] Serrana State Hosp, Serrana, SP - Brazil
[2] Epidem Serv, Serrana, SP - Brazil
[3] Hlth Dept, Serrana, SP - Brazil
[4] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto, SP - Brazil
[5] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Med Imaging Hematol & Clin Oncol, Ribeirao Preto, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Brazilian Journal of Infectious Diseases; v. 25, n. 2 MAR-APR 2021.
Web of Science Citations: 0
Abstract

ABSTRACT SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities (SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with chronic health conditions. Following identification of COVID-19 index case in a SNF, serial point-prevalence was implemented with reverse transcription–polymerase chain reaction (RT-PCR) and immunochromatographic assays. Active surveillance and early isolation of infected patients were implemented. Out of 23 SNF residents and 26 healthcare workers (HCW), 18 (78%) and 12 (46%) tested positive for SARS-CoV-2, respectively. High proportion (38%) of positive patients were asymptomatic and RT-PCR was positive up to six days before symptoms. Five (21.74%) residents were hospitalized with COVID-19, and 2 (9%) died; only 1 (4%) HCW needed to be hospitalized and no staff members died. Active surveillance helped COVID-19 control and management in a SNF. Testing symptomatic individuals only may fail to identify and isolate all persons contributing to transmission. In high-risk elderly, only symptoms screening may not be enough for outbreak control. (AU)

FAPESP's process: 20/05367-3 - Convalescent donor plasma to treat patients with severe SARS-CoV-2 infection (COVID-19)
Grantee:Rodrigo do Tocantins Calado de Saloma Rodrigues
Support Opportunities: Regular Research Grants