Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol

Full text
Author(s):
Peres, Matheus Ruffo [1] ; Pastrello, Bruna [1] ; Sambrano, Julio Ricardo [2] ; Morgon, Nelson Henrique [3] ; de Souza, Aguinaldo Robinson [1] ; Ximenesa, Valdecir Farias [1]
Total Authors: 6
Affiliation:
[1] Univ Estadual Sao Paulo, Fac Ciencias, Dept Quim, BR-17033360 Bauru, SP - Brazil
[2] Univ Estadual Sao Paulo, Fac Ciencias, Dept Matemat, BR-17033360 Bauru, SP - Brazil
[3] Univ Estadual Campinas, Inst Quim, Dept Fis Quim, BR-13083861 Campinas, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS; v. 24, n. 1 2021.
Web of Science Citations: 0
Abstract

Titanium dioxide (TiO2) and zinc oxide (ZnO) are among the most used catalysts in photodegradation. Paracetamol and salicylic acid are widely used as pharmaceutical drugs. We found that paracetamol is less susceptible to photodegradation compared to salicylic acid. From a chemical perspective, this was not expected since paracetamol is more vulnerable to chemical oxidation. Aiming the comprehension of this phenomenon, studies were performed comparing the efficiency of photodegradation of paracetamol versus salicylic acid and acetophenone versus 4-aminoacetophenone. The presence of amino/amide group decreased the efficiency of degradation significantly. It was also found that salicylic acid improved the degradation of paracetamol when both compounds were present in the reaction medium. The lower efficiency of photodegradation of the amino-based compounds seems to be related to the deactivation of the excited states of the TiO2 and ZnO. Theoretical calculations at the TD-PBE0/6-311++G(3df,2p) high level were performed and corroborated our proposal. (AU)

FAPESP's process: 16/20549-5 - Development and application of fluorescent probes and probes based on circular dichroism for the interaction studies of ligands with protein, characterization of amyloid proteins and determination of enzymatic activity
Grantee:Valdecir Farias Ximenes
Support Opportunities: Regular Research Grants