Innovative extraction materials for fiber-in-tube solid phase microextraction: A review

Author(s)

Souza, Israel D. ^[1] ; Oliveira, Igor G. C. ^[1] ; Queiroz, Maria Eugenia C. ^[1]

Affiliation

^[1] Univ Sao Paulo, Dept Quim, Fac Filosofia Ciencias & Letras Ribeirao Preto, Ribeirao Preto, SP - Brazil

• Document type: Review article
• Source: Analytica Chimica Acta; v. 1165, JUN 22 2021.
• Web of Science Citations: 1

Abstract

Fiber-in-tube solid-phase microextraction (fiber-in-tube SPME) with short capillary longitudinally packed with fine fibers as extraction device allows direct coupling to high performance liquid chromatography (HPLC) systems to determine weakly volatile or thermally labile compounds. This technique associates the advantages of miniaturized and analytical on-line systems. Major achievements include the use of different capillaries (fused-silica, copper, stainless steel, polyetheretherketone (PEEK), or poly(tetrafluoroethylene) (PTFE)) that are packed with neat fibers (Zylon (R), silk, or Kevlar 29 (R)) or fibers (stainless steel, basalt, or carbon) functionalized with selective coatings (aerogels, ionic liquids (ILs), polymeric ionic liquids (PILs), molecularly imprinted polymers (MIPs), layered double hydroxides (LDHs), or conducting polymer). This review outlines the fundamental theory and the innovative extraction materials for fiber-in-tube SPME-HPLC systems and highlights their main applications in environmental and bioanalyses. (C) 2020 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 20/00126-8 - Development of the methods of the microextraction hyphenated with LC-MS/MS or directly to MS/MS for the determination of biomarkers in biological samples of patient or rats with neurodegenerative diseases
• Grantee: Maria Eugênia Queiroz Nassur
• Support Opportunities: Regular Research Grants
• FAPESP's process: 18/06068-0 - Development of the column switching SALLE-UHPLC-MS/MS method to anandamide and 2-arachidonoylglycerol determination in brain samples of rats submitted to an animal model of Parkinsons Disease
• Grantee: Igor Gustavo de Carvalho Oliveira
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 17/02147-0 - Single drop chromatography and its coupling to mass spectrometry: instrumental strategies, development of materials, automation and analytical applications
• Grantee: Fernando Mauro Lanças
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/19485-0 - Development of nitinol fiber chemically coated with zwitterionic polymeric ionic liquids for determination of beta-amyloids in plasma samples from patients with Alzheimer's disease by direct coupling fiber-in-tube SPME and MS/MS
• Grantee: Israel Donizeti de Souza
• Support Opportunities: Scholarships in Brazil - Post-Doctoral