| Full text | |
| Author(s): |
Silva-Pinto, Ana Cristina
[1, 2]
;
Santos-Oliveira, Leticia
[2]
;
Souza Santos, Flavia Leite
[1, 2]
;
Haddad, Simone Kashima
[1]
;
De Santis, Gil Cunha
[1, 2]
;
Calado, Rodrigo do Tocantins
[1, 2]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Reg Blood Ctr, Ribeirao Preto Sch Med, Sao Paulo - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Med Imaging Hematol & Oncol, Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Acta Haematologica; SEP 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Sickle cell disease is characterized by vaso-occlusive phenomena and haemolytic anaemia. There is a significant concern that the overlap of COVID-19 lung disease with acute chest syndrome that occurs in sickle cell patients may result in serious complications. Case reports of sickle cell patients with COVID-19 have been published. Here, we present a case series of COVID-19 infection in sickle cell patients in a developing country (Brazil). Only 10 patients tested positive so far for SARS-CoV-2 of 600 patients followed at our institution, of which 8 needed hospitalization (one in the intensive care unit), with no deaths. Even in a middle-income country, COVID-19 was reported to be relatively mild in sickle cell patients. In relation to risk factors, blood type O seems to confer some protection against developing severe COVID-19, a finding that could guide clinicians to adopt more clinical surveillance for patients with non-O blood type in sickle cell patients. (AU) | |
| FAPESP's process: | 20/05367-3 - Convalescent donor plasma to treat patients with severe SARS-CoV-2 infection (COVID-19) |
| Grantee: | Rodrigo do Tocantins Calado de Saloma Rodrigues |
| Support Opportunities: | Regular Research Grants |