Optimizing phase variability threshold for automated synchrogram analysis of cardiorespiratory interactions in amateur cyclists

Author(s):Show less -

Cairo, Beatrice ^[1] ; de Abreu, Raphael Martins ^[2] ; Bari, Vlasta ^[3] ; Gelpi, Francesca ^[3] ; De Maria, Beatrice ^[4] ; Rehder-Santos, Patricia ^[2] ; Sakaguchi, Camila Akemi ^[2] ; da Silva, Claudio Donisete ^[2] ; Signini, Etore De Favari ^[2] ; Catai, Aparecida Maria ^[2] ; Porta, Alberto ^{[3, 1]}

Affiliation

^[1] Univ Milan, Dept Biomed Sci Hlth, I-20133 Milan - Italy

^[2] Univ Fed Sao Carlos, Dept Phys Therapy, BR-13565905 Sao Carlos, SP - Brazil

^[3] IRCCS Policlin San Donato, Dept Cardiothorac Vasc Anesthesia & Intens Care, I-20097 Milan - Italy

^[4] IRCCS Ist Clin Sci Maugeri, I-20138 Milan - Italy

• Document type: Journal article
• Source: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND; v. 379, n. 2212 DEC 13 2021.
• Web of Science Citations: 1

Abstract

We propose a procedure suitable for automated synchrogram analysis for setting the threshold below which phase variability between two marker event series is of such a negligible amount that the null hypothesis of phase desynchronization can be rejected. The procedure exploits the principle of maximizing the likelihood of detecting phase synchronization epochs and it is grounded on a surrogate data approach testing the null hypothesis of phase uncoupling. The approach was applied to assess cardiorespiratory phase interactions between heartbeat and inspiratory onset in amateur cyclists before and after 11-week inspiratory muscle training (IMT) at different intensities and compared to a more traditional approach to set phase variability threshold. The proposed procedure was able to detect the decrease in cardiorespiratory phase locking strength during vagal withdrawal induced by the modification of posture from supine to standing. IMT had very limited effects on cardiorespiratory phase synchronization strength and this result held regardless of the training intensity. In amateur athletes training, the inspiratory muscles did not limit the decrease in cardiorespiratory phase synchronization observed in the upright position as a likely consequence of the modest impact of this respiratory exercise, regardless of its intensity, on cardiac vagal control. This article is part of the theme issue `Advanced computation in cardiovascular physiology: new challenges and opportunities'. (AU)

• FAPESP's process: 16/22215-7 - Impact of inspiratory muscle training and aging on metabolic mapping, autonomic modulation, and cardiovascular, respiratory and metabolic responses, and prediction of cardiorespiratory health through wearables
• Grantee: Aparecida Maria Catai
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 17/13402-0 - Comparison of different intensities of inspiratory muscle training on the cardiovascular autonomic control of cyclists: controlled and randomized clinical study
• Grantee: Raphael Martins de Abreu
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 18/11123-0 - Innovative analysis of cardiovascular autonomic control in cyclists after different intensities of inspiratory muscle training: controlled and randomized clinical study
• Grantee: Raphael Martins de Abreu
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate (Direct)