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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

requency of respiratory pathogens other than SARS-CoV-2 detected COVID-1

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Boschiero, Matheus Negri [1, 2] ; Duarte, Aires [3] ; Capasso Palamim, Camila Vantini [1, 2] ; Alvarez, Alfonso Eduardo [4] ; Mauch, Renan Marrichi [5] ; Lima Marson, Fernando Augusto [1, 2]
Total Authors: 6
[1] Univ Sao Francisco, Lab Cell & Mol Tumor Biol & Bioact Cpds, Braganca Paulista, SP - Brazil
[2] Univ Sao Francisco, Lab Human & Med Genet, Braganca Paulista, SP - Brazil
[3] Univ Lisbon, Fac Sci, BioISI Biosyst & Integrat Sci Inst, Lisbon - Portugal
[4] Pulmonol & Allergy Pediat Ctr, Campinas, SP - Brazil
[5] Univ Estadual Campinas, Sch Med Sci, Ctr Invest Pediat, Campinas, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Web of Science Citations: 0

The frequencies of 19 respiratory pathogens other than SARS-CoV-2 were assessed in 6,235 Brazilian individ-uals tested for COVID-19. Overall, only 83 individuals who tested positive for SARS-CoV-2 had codetection of other pathogens. Individuals infected with Rhinovirus/Enterovirus, Human Coronavirus (HCoV)-HKU1, HCoV-NL63, HPIV-4, Influenza A (-H1N1 and other subtypes), Influenza B, Human Respiratory Syncytial Virus and Human Metapneumovirus were less likely to test positive for SARS-CoV-2. Infection with Streptococcys pyogenes, Chlamydophila pneumoniae, Mycoplasma pneumoniae, and Bordetella pertussis were more frequent in individuals who tested negative for SARS-CoV-2, but without significancy. We found 150 individuals infected with >= 2 pathogens other than SARS-CoV-2, only 3 out of whom tested positive for COVID-19. The codetection frequency was low in individuals diagnosed with COVID-19. Other viral infections may provide a cross-reactive, protective immune response against SARS-CoV-2. Screening for bacterial respiratory infec-tions upon COVID-19 testing is important to drive suitable therapeutic approaches and avoid unnecessary antibiotic prescription. (c) 2021 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 21/05810-7 - Down syndrome in COVID-19: an observational study of the first year of the pandemic in Brazil
Grantee:Matheus Negri Boschiero
Support Opportunities: Scholarships in Brazil - Scientific Initiation