Morphogenesis in Synthetic Chemical Cells

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Author(s):	Silva-Dias, Leonardo ; Lopez-Castillo, Alejandro Total Authors: 2
Document type:	Journal article
Source:	Journal of Physical Chemistry Letters; v. 13, n. 1, p. 6-pg., 2022-01-06.
Abstract
We present an efficient model for describing morphogenesis and the emergence of spatiotemporal structures in synthetic chemical cells. This work is motivated by an experimental setup used for testing Turing's theory of morphogenesis. The model developed is based on the general theory of chemically active droplets, which combines the classical theory of phase separation with reaction-diffusion systems. Through the 2D calculations, we find the six spatiotemporal structures predicted by Turing in 1952 and experimentally observed, in a 1D array of droplets. Moreover, under Turing instability, with a determined chemical wavelength, the system undergoes morphogenesis. This theoretical approach provides a useful tool for understanding the physical differentiation through the direct calculation of the osmotic pressure in each cell as the chemical reaction occurs. (AU)

FAPESP's process:	19/12501-0 - Theoretical study of bidimensional systems
Grantee:	Alejandro López Castillo
Support Opportunities:	Regular Research Grants


FAPESP's process:	19/23205-3 - Theoretical study of the complex kinetics of catalytic processes
Grantee:	Leonardo Silva Dias
Support Opportunities:	Scholarships in Brazil - Doctorate