Effect of arginine on microorganisms involved in dental caries: a systematic literature review ofin vitrostudies

Author(s)

Miranda, Marina Lins ; Silva, Bianca Nubia Souza ; Salomao, Karina Borges ; de Oliveira, Analu Barros ; Gabbai-Armelin, Paulo Roberto ; Brighenti, Fernanda Lourencao

• Document type: Journal article
• Source: BIOFOULING; v. 36, n. 6, p. 14-pg., 2020-08-04.

Abstract

This systematic review aimed to discuss the effects of arginine on caries-related microorganisms in differentin vitrobiofilm models. The eligibility criteria werein vitrostudies that evaluated the effect of arginine at different concentrations on caries-related microorganisms using biofilm models. Eighteen studies published between 2012 and 2019 were included. Different bacterial species were studied. Seventeen studies (94.4%) achieved a low risk of bias and only one showed a medium risk of bias. The studies showed that arginine is a promising approach for the ecological management of dental caries. The focus of this review was to evaluate the effects of arginine on microorganisms involved in the mechanism of dental caries. (AU)

• FAPESP's process: 18/18440-0 - Bioprospection of natural products in photodynamic therapy against microorganisms of medial and dental importance
• Grantee: Analú Barros de Oliveira
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 13/12326-8 - Microbial interactions between cariogenic bacteria: evaluation of growth, metabolic activity, biochemical composition and susceptibility to chlorhexidine of biofilms formed in vitro
• Grantee: Fernanda Lourenção Brighenti
• Support Opportunities: Regular Research Grants