Copper-catalyzed N-H insertion reactions from sulfoxonium ylides

Author(s)

Furniel, Lucas G. ; Burtoloso, Antonio C. B.

• Document type: Journal article
• Source: Tetrahedron; v. 76, n. 51, p. 10-pg., 2020-12-18.

Abstract

The first use of copper(II) as an efficient catalyst for N-H insertion reactions between anilines and alpha-carbonyl sulfoxonium ylides is described. Products, 39 arylglycine derivatives, were obtained in yields up to 97% employing a simple and fast experimental procedure. (C) 2020 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 17/23329-9 - Synthesis of substituted cyclopentanes and long chain polyols from abundant chemical platforms derived from biomass
• Grantee: Antonio Carlos Bender Burtoloso
• Support Opportunities: Regular Research Grants
• FAPESP's process: 18/17800-3 - New methodologies using sulfur ylides for the enantioselective alpha-Heterofunctionalization of carbonyl compounds
• Grantee: Lucas Giani Furniel
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 13/18009-4 - Molecular design, synthesis and trypanocidal activity of cruzain reversible covalent inhibitors
• Grantee: Carlos Alberto Montanari
• Support Opportunities: Research Projects - Thematic Grants