Cardiovascular, Respiratory, and Functional Effects of Home-Based Exercise Training after COVID-19 Hospitalization

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Do Amaral, Vanessa Teixeira ; Viana, Ariane Aparecida ; Heubel, Alessandro Domingues ; Linares, Stephanie Nogueira ; Martinelli, Bruno ; Camprigher Witzler, Pedro Henrique ; De Oliveira, Gustavo Yudi Orikassa ; Zanini, Gabriel De Souza ; Silva, Audrey Borghi ; Mendes, Renata Goncalves ; Ciolac, Emmanuel Gomes

• Document type: Journal article
• Source: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE; v. 54, n. 11, p. 9-pg., 2022-11-01.

Abstract

Introduction The present randomized, single-center, and single-blinded clinical trial tested the hypothesis that tele-supervised home-based exercise training (exercise) is an effective strategy for improving cardiovascular, respiratory, and functional capacity parameters in individuals who were hospitalized due to coronavirus disease 2019 (COVID-19). Methods Thirty-two individuals (52 +/- 10 yr; 17 were female) randomly assigned to exercise (n = 12) or control groups (n = 20) had their anthropometric (weight, body mass index), hemodynamic (brachial and central blood pressure), vascular (arterial stiffness), ventilatory (pulmonary function and respiratory muscle strength), and functional parameters (handgrip strength, five-time sit to stand, timed up and go test, and 6-min walking test) assessed at baseline (30-45 d of hospital discharged) and after 12 wk of follow-up. Results Both groups similarly increased (P < 0.001) forced vital capacity (absolute and percent of predicted), forced expiratory volume in the first second (absolute and percent of predicted), and handgrip strength during follow-up. However, only the exercise group reduced carotid-femoral pulse wave velocity (-2.0 +/- 0.6 m center dot s(-1), P = 0.048) and increased (P < 0.05) resting oxygen saturation (1.9% +/- 0.6%), mean inspiratory pressure (24.7 +/- 7.1 cm H2O), mean expiratory pressure (20.3 +/- 5.8 cm H2O), and percent of predicted mean expiratory pressure (14% +/- 22%) during follow-up. No significant changes were found in any other variable during follow-up. Conclusions Present findings suggest that tele-supervised home-based exercise training can be a potential adjunct therapeutic to rehabilitate individuals who were hospitalized due to COVID-19. (AU)

• FAPESP's process: 17/25648-4 - Effect of heated water-based versus land-based exercise training on hemodynamic variables, functional capacity and quality of life in older hypertensive individuals
• Grantee: Emmanuel Gomes Ciolac
• Support Opportunities: Regular Research Grants