Effects of a home-based exercise-training program on functional capacity among COVID-19 surviors: a randomized controlled clinical trial

• Grant number: 20/15678-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): February 01, 2022
• Effective date (End): September 30, 2023
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Karla Fabiana Goessler
• Grantee: Matheus Molina Meletti
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Worldwide more than 1.300.000 of deaths were attributed to severe acute respiratory syndrome induced by the new coronavirus (SARS-CoV-2), which has been declared a pandemic. A portion of patients infected with SARS-CoV-2 (~ 20%) have severe respiratory symptoms which require intensive therapy with oxygen support increasing hospital length to treat the disease. Thus, the present project aims to evaluate the effect of a home-based exercise training program on functional capacity in COVID-19 survivors. To this end, a randomized controlled clinical trial will be conducted, in which patients will be randomized to the intervention (home-based exercise training program) or control (conventional post-treatment) groups. Before and after the intervention period (12 weeks), patients will be assessed for functional capacity, through physical tests and questionnaires. At the end of the 12-week intervention, it is expected that patients allocated to the home-based program will improve functional capacity compared to patients in the control group.(AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LONGOBARDI, IGOR; DO PRADO, DANILO MARCELO LEITE; GOESSLER, KARLA FABIANA; MELETTI, MATHEUS MOLINA; DE OLIVEIRA JUNIOR, GERSIEL NASCIMENTO; DE ANDRADE, DANIELI CASTRO OLIVEIRA; GUALANO, BRUNO; ROSCHEL, HAMILTON. Oxygen uptake kinetics and chronotropic responses to exercise are impaired in survivors of severe COVID-19. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 323, n. 3, p. 8-pg., 2022-09-01. (20/15678-6, 19/25032-9, 20/07540-4)

ESTEVES, GABRIEL P.; NOVELLI, FABIULA ISOTON; MELETTI, MATHEUS MOLINA; COSTA, LUIZ AUGUSTO RIANI; DO PRADO, DANILO MARCELO LEITE; MOLLER, GABRIELLA BERWIG; MARTICORENA, FELIPE MIGUEL; FRANCO, RUTH ROCHA; COMINATO, LOUISE; DOS SANTOS, CLAUDIA RENATA PINTO; et al. Cloth masks during exercise are safe and tolerable for children with overweight and obesity. PEDIATRIC PULMONOLOGY, v. 58, n. 7, p. 4-pg., 2023-05-03. (21/05847-8, 19/18039-7, 17/13552-2, 20/07860-9, 20/15678-6)

LONGOBARDI, IGOR; GOESSLER, KARLA; DE OLIVEIRA JR, GERSIEL NASCIMENTO; DO PRADO, DANILO MARCELO LEITE; SANTOS, JHONNATAN VASCONCELOS PEREIRA; MELETTI, MATHEUS MOLINA; DE ANDRADE, DANIELI CASTRO OLIVEIRA; GIL, SAULO; BOZA, JOAO ANTONIO SPOTT DE OLIVEIRA; LIMA, FERNANDA RODRIGUES; et al. Effects of a 16-week home-based exercise training programme on health-related quality of life, functional capacity, and persistent symptoms in survivors of severe/critical COVID-19: a randomised controlled trial. BRITISH JOURNAL OF SPORTS MEDICINE, v. N/A, p. 10-pg., 2023-05-09. (20/08091-9, 19/18039-7, 17/13552-2, 21/13580-1, 20/15678-6, 20/07540-4)