Advanced search
Start date
Betweenand


H-F bond insertions into alpha-diazo carbonyl compounds

Full text
Author(s):
Munaretto, Laieli S. ; Gallo, Rafael D. C. ; Leao, Luiz Paulo M. O. ; Jurberg, Igor D.
Total Authors: 4
Document type: Journal article
Source: ORGANIC & BIOMOLECULAR CHEMISTRY; v. 20, n. 31, p. 5-pg., 2022-03-24.
Abstract

A reaction for H-F bond insertion into alpha-diazo carbonyl compounds is reported. The protocol describes a simple reaction setup employing commercially available HF center dot pyr (Olah reagent) as the fluorine source. The method is rapid and practical, and allows access to a broad range of alpha-fluorinated carbonyl compounds in generally good yields. (AU)

FAPESP's process: 20/00144-6 - Structural proteomics: design, synthesis and application of new generation crosslinking agents
Grantee:Rafael Douglas Clemente Gallo
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 19/01235-8 - Photochemistry with visible light using donor-acceptor diazocompounds
Grantee:Igor Dias Jurberg
Support Opportunities: Regular Research Grants