Non-destructive biomarkers can reveal effects of the association of microplastics and pharmaceuticals or personal care products

Author(s)

da Silva, Leticia Fernanda ; Nobre, Caio Rodrigues ; Moreno, Beatriz Barbosa ; Seabra Pereira, Camilo Dias ; de Souza Abessa, Denis Moledo ; Choueri, Rodrigo Brasil ; Gusso-Choueri, Paloma Kachel ; Cesar, Augusto

• Document type: Journal article
• Source: Marine Pollution Bulletin; v. 177, p. 10-pg., 2022-03-04.

Abstract

Methods to assess the effects of contaminants on marine organisms typically involve euthanasia to obtain samples, but less invasive techniques may be more appropriate for working with threatened species. In this study, were assessed the biological responses of crabs exposed to microplastics and contaminants of emerging concern. Biochemical and cellular effects (lipid pemxidation, DNA damage, cholinesterase activity, and lysosomal membrane stability) in hemolymph were analyzed in a kinetic study, at 3 and 7 days, in U. cordatus exposed to microplastics spiked with Triclosan (TCS) or 17 alpha-Ethynylestradiol (EE2). The results showed that the contaminants were produced toxic effects in the crabs exposed either to the microplastics alone (oxidative stress, genotoxicity, and neurotoxicity), or to micmplastics with TCS or EE2 adsorbed (neumtoxic and cytotoxic). The present study showed the responsiveness of non-lethal analyzes to understanding the biological effects of combined exposure to micmplastics and chemical pollution. (AU)

• FAPESP's process: 17/07353-7 - ASSESSMENT OF THE EFFECTS OF OCEAN ACIDIFICATION ON THE BIOAVAILABILITY OF EMERGING POLLUTANTS - ACIDOCEAN
• Grantee: Augusto Cesar
• Support Opportunities: Regular Research Grants
• FAPESP's process: 17/04970-5 - Relationship between metal concentrations in the sediment, bioaccumulation and toxic responses in p. vivipara:subsidies for the environmental risk assessment
• Grantee: Paloma Kachel Gusso Choueri
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 17/12193-9 - EVALUATION OF THE ENVIRONMENTAL RISK OF THE INTERACTION OF MICROPLASTIC, DRUG AND ANTIMICROBIAL: AN ECOTOXICOLOGICAL APPROACH
• Grantee: Caio Rodrigues Nobre
• Support Opportunities: Scholarships in Brazil - Doctorate