Meteorological parameters and hospitalizations of patients with sickle cell anemia: a 20-year retrospective study in Campinas, Sao Paulo, Brazil

Author(s)

Alagbe, Adekunle Emmanuel ; Corozolla, Welington ; Teixeira, Liriam Samejima ; Coelho, Raissa Peres ; Heuminski de Avila, Ana Maria ; Paro Costa, Paula Dornhofer ; Sonati, Maria Fatima ; de Faria, Eliana Cotta ; Nunes Dos Santos, Magnun Nueldo

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH; v. N/A, p. 13-pg., 2022-07-29.

Abstract

To investigate the influence of climate on hospitalizations of sickle cell anemia (SCA) adults and children, we analyzed the health and meteorological parameters from a metropolis (1999-2018). 1462 hospitalizations were coded for SCA patients in crisis (M:F = 715:747) and 1354 hospitalizations for SCA patients without crisis (M:F = 698:656) [age = 22.9 vs 15.2 years and duration of hospitalization (DoH) = 5.7 vs 4.4 days, respectively,]. More hospitalizations were for adults than children in crisis, and for children than adults without crisis. More children and adults were hospitalized in winter andspring than in summer and autumn Hospitalizations correlated positively with humidity (lag -5), maximum pressure (lag -2), mean pressure (lag -2), and thermal amplitude (lag -2), and negatively with maximum temperature (lag -3). DoH positively correlated with minimum temperature (lag -4). Understanding these complex associations would induce attitudinal/behavioral modifications among patients and their caregivers. (AU)

• FAPESP's process: 17/20013-0 - Human health and adaptation to climate change in Brazil: a data science approach
• Grantee: Eliana Cotta de Faria
• Support Opportunities: Research Program on Global Climate Change - Regular Grants