Development of Electrochemical Platform Based on Molecularly Imprinted Poly(methacrylic acid) Grafted on Iniferter-modified Carbon Nanotubes for 17β-estradiol Determination in Water Samples

Author(s)

Marques, Gabriel Lopes ; Rocha, Luana Rianne ; Prete, Maiyara Carolyne ; Gorla, Felipe Augusto ; Moscardi dos Santos, Dayana ; Segatelli, Mariana Gava ; Teixeira Tarley, Cesar Ricardo

• Document type: Journal article
• Source: Electroanalysis; v. 33, n. 3, p. 11-pg., 2020-10-23.

Abstract

This paper describes the development of a new electrochemical sensor for 17 beta-estradiol (E2) determination based on glassy carbon electrode (GCE) modified with molecularly imprinted polymer grafted onto iniferter-multiwall carbon nanotubes surface (MIP-MWCNT) and dihexadecyl-hydrogen-phosphate (DHP). The electrochemical method was based on closed-circuit preconcentration of E2 in 0.1 mol L-1 phosphate buffer (pH 7.0) during 500 s. Upon preconcentration, E2 was determined by differential pulse voltammetry (DPV) exhibiting a limit of detection of 0.01 mu mol L-1. The sensor exhibited higher selectivity toward E2 and it was applied for E2 determination in natural water samples, with accuracy attested by HPLC-DAD. (AU)

• FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Research Projects - Thematic Grants