| Full text | |
| Author(s): Show less - |
Kobayashi, Gerson S.
;
Vieira-Silva, Gleiciele A.
;
Varella-Branco, Elisa
;
Moreira, Danielle P.
;
Kitajima, Joao Paulo F. W.
;
Hemza, Claudia R. M. L.
;
Mingroni-Netto, Regina C.
;
Lojudice, Fernando H.
;
Oiticica, Jeanne
;
Bento, Ricardo F.
;
Batissoco, Ana C.
;
Lezirovitz, Karina
Total Authors: 12
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| Document type: | Journal article |
| Source: | STEM CELL RESEARCH; v. 71, p. 5-pg., 2023-09-01. |
| Abstract | |
The DFNA58 locus contains a genomic duplication involving three protein-coding genes (CNRIP1, PLEK, and PPP3R1 & PRIME;s exon 1) and other uncharacterized lncRNA genes (LOC101927723, LOC107985892 and LOC102724389). To clarify the role of these genes in hearing and precisely determine their role in hearing loss, four iPSC lines were generated from two carriers and two noncarriers of the duplication. (AU) | |
| FAPESP's process: | 13/08028-1 - CEGH-CEL - Human Genome and Stem Cell Research Center |
| Grantee: | Mayana Zatz |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |
| FAPESP's process: | 18/03433-9 - 145/5000 Use of IPS cells and animal models to elucidate the pathophysiology of post-lingual sensorineural hearing loss of genetic etiology |
| Grantee: | Karina Lezirovitz Mandelbaum |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 14/13071-6 - Identification of novel genes and functional studies in nonsyndromic deafness |
| Grantee: | Karina Lezirovitz Mandelbaum |
| Support Opportunities: | Regular Research Grants |