Assessing the chemical composition, potential toxicity and cancer risk of airborne fine particulate matter (PM2.5) near a petrochemical industrial area

Author(s)

Caumo, Sofia ; Yera, Aleinnys B. ; Alves, Celia ; Rienda, Ismael Casotti ; Kovats, Nora ; Hubai, Katalin ; Vasconcellos, Perola de Castro

• Document type: Journal article
• Source: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 101, p. 11-pg., 2023-06-19.

Abstract

In the vicinity of a petrochemical industrial region in Sa & SIM;o Paulo, Brazil, PM2.5-bound organic carbon (OC), elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs, oxy-PAHs, hopanes, and inorganic species were evaluated. Oxidative potential (OP), burden (OB), and Alivibrio fischeri bioluminescence inhibition (AFBIA) assays were conducted to determine the potential health effects of exposure to these compounds. The PM2.5 mean concentration was 32.0 & PLUSMN; 18.2 & mu;g m  3, and benzo (a)pyrene was found to exceed recommended levels by at least four times. Secondary sources and vehicular emissions were indicated by nitro-PAHs, oxy-PAHs, and inorganic species. The OP and OB results revealed that secondary compounds favored antioxidant depletion. The AFBIA results showed that 64 % of the samples were toxic. These findings emphasize the need to reduce the exposure risk and take measures to protect human health. (AU)

• FAPESP's process: 16/23339-1 - Molecular characterization and occurrence of organic compounds in gaseous and particulate phase in atmospheric particulate matter collected in Petrochemical Industry of Capuava (SP)
• Grantee: Sofia Ellen Caumo Miranda
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)