| Full text | |
| Author(s): Show less - |
Shida, Thiago Kenzo Fujioka
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de Oliveira, Claudia Eunice Neves
;
de Campos, Debora da Silva Fragoso
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Los Angeles, Emanuele
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Bernardo, Claudionor
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de Oliveira, Luana dos Santos
;
Silva, Layla Cupertino Salloum e
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Novaes, Thayna Magalhaes
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Shokur, Solaiman
;
Bouri, Mohamed
;
Coelho, Daniel Boari
Total Authors: 11
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| Document type: | Journal article |
| Source: | Neuroscience Letters; v. 806, p. 6-pg., 2023-04-15. |
| Abstract | |
Introduction: This study aims to evaluate the effects of medication, and the freezing of gait (FoG) on the kinematic and kinetic parameters of gait in people with Parkinson's disease (pwPD) compared to neurologically healthy. Methods: Twenty-two people with a clinical diagnosis of idiopathic PD in ON and OFF medication (11 FoG), and 18 healthy participants (control) were selected from two open data sets. All participants walked on the floor on a 10-meter-long walkway. The joint kinematic and ground reaction forces (GRF) variables of gait and the clinical characteristics were compared: (1) PD with FoG (pwFoG) and PD without FoG (pwoFoG) in the ON condition and control; (2) PD with FoG and PD without FoG in the OFF condition and control; (3) Group (PD with FoG and PD without FoG) and Medication. Results: (1) FoG mainly affects distal joints, such as the ankle and knee; (2) PD ON showed changes in the range of motion of both distal and proximal joints, which may explain the increase in step length and gait speed expected with the use of L-Dopa; and (3) the medication showed improvements in the kinematic and kinetic parameters of the gait of people with pwFoG and pwoFoG equally; (4) pwPD showed a smaller second peak of the vertical component of the GRF than the control. Conclusion: The presence of FoG mainly affects distal joints, such as the ankle and knee. PD presents a lower application of GRF during the impulse period than healthy people, causing lower gait performances. (AU) | |
| FAPESP's process: | 19/06604-1 - Biomechanical modelling and clinical assessment data gathering with technological innovations towards movement restoration and sports performance for people with disabilities |
| Grantee: | Claudiane Arakaki Fukuchi |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |