AGN simulation and validation model

Author(s)

Lopes, Fabricio M. ; Cesar, Roberto M., Jr. ; Costa, Luciano da F. ; Bazzan, ALC ; Craven, M ; Martins, NF

• Document type: Journal article
• Source: Lecture Notes in Computer Science; v. 5167, p. 3-pg., 2008-01-01.

Abstract

An important question in computational biology is how genes are regulated and interact through gene networks. Some methods for the identification of gene networks from temporal data were proposed. An important open problem regards how to validate such resulting networks. This work presents an approach to validate such algorithms, considering three main aspects: (1) AGN model generation and simulation; (2) gene network identification; (3) validation of identified network. (AU)

• FAPESP's process: 05/00587-5 - Mesh (graph) modeling and techniques of pattern recognition: structure, dynamics and applications
• Grantee: Roberto Marcondes Cesar Junior
• Support Opportunities: Research Projects - Thematic Grants