Simple Electroanalytical Method for Determination of Guanosine in Biological Sample

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Author(s):	dos Santos, Daniela Pereira ; Totta Brunelli, Tamara Fernanda ; Bianchi, Alex Rodrigo ; Boldrin Zanoni, MariaValnice Total Authors: 4
Document type:	Journal article
Source:	ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY; v. 2, n. 4, p. 10-pg., 2010-12-01.
Abstract
A poly glutamic acid film modified electrode exhibited a catalytic response to guanosine oxidation potential and higher peak current value. Linear concentration curve was obtained in the concentration interval of 1.0 a 10.0 mu mol L-1 in 0.04 mol L-1 B-R buffer pH 2.0 with a detection limit of 0.198 mu mol L-1. The electrode was used for the determination of guanosine in the potential of + 1.1 V (vs. Ag/AgCl) using differential pulse voltammetry (DPV) at urine sample with good recovery. (AU)