FCGR3B*03 allele inheritance pattern in Brazilian families and some new variants of gene FCGR3B

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Author(s):	Terzian, Claudia C. N. ; Chiba, Akemi K. ; Santos, Viviani C. ; Silva, Neusa P. ; Bordin, Jose O. Total Authors: 5
Document type:	Journal article
Source:	Transfusion; v. 52, n. 3, p. 6-pg., 2012-03-01.
Abstract
BACKGROUND: The FCGR3B gene encoding the FcyRIIIb receptor for immunoglobulin G has three polymorphic forms known as HNA-1a, HNA-1b, and HNA-1c, encoded by the alleles FCGR3B01, FCGR3B02, and FCGR3B03, respectively. It is not clear whether the inheritance of the FCGR3B03 allele, which encodes the HNA-1c, is linked or not to the other two alleles. The objective of this study was to identify the inheritance pattern of the FCGR3B*03 allele in Brazilians. (AU)

FAPESP's process:	05/55237-9 - Clinical and molecular aspects of antigens and antibodies of blood cells
Grantee:	Jose Orlando Bordin
Support Opportunities:	Research Projects - Thematic Grants