| Full text | |
| Author(s): |
Oliveira, F. L.
;
Huber, P. C.
;
Almeida, W. P.
;
Sabino, J. R.
;
Aparicio, R.
Total Authors: 5
|
| Document type: | Journal article |
| Source: | ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS; v. 69, p. 13-pg., 2013-02-01. |
| Abstract | |
The Zn-II center in the dicationic complex of the title compound, [Zn(C10H7N3S)(3)](NO3)(2)center dot 0.5C(2)H(5)OH center dot H2O, is in a distorted octahedral environment with imperfect noncrystallographic C-3 symmetry. Each 2-(1,3-thiazol-2-yl)-1H-benzimidazole ligand coordinates in a bidentate manner, with the Zn-N(imidazole) bond lengths approximately 0.14 angstrom shorter than the Zn-N(thiazole) bond lengths. Charge-assisted hydrogen bonds connect cations, anions and water molecules. A lattice void is occupied by an ethanol solvent molecule disordered about a crystallographic inversion center and pi-stacking is observed between one type of symmetry-related benzene rings. (AU) | |
| FAPESP's process: | 10/20861-2 - Development of candidate drugs for the treatment of Alzheimer's disease. I. investigation of metal chelators as inhibitors of the beta-amyloid aggregation; II. Development of tacrine-ibuprofen hybrids |
| Grantee: | Wanda Pereira Almeida |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 09/51602-5 - Chemical biology: new natural and synthetic molecular targets against cancer, structural studies, biological evaluation and mode of action |
| Grantee: | Ronaldo Aloise Pilli |
| Support Opportunities: | Research Projects - Thematic Grants |