bgb Evaluation of trabecular microarchitecture of normal osteoporotic and osteopenic human vertebrae

Author(s)

Cesar, R. ; Boffa, R. S. ; Fachine, L. T. ; Leivas, T. P. ; Silva, A. M. H. ; Pereira, C. A. M. ; Reiff, R. B. M. ; Rollo, J. M. D. A. ; Bartolo, P ; Fernandes, P

• Document type: Journal article
• Source: X INTERNATIONAL CONFERENCE ON STRUCTURAL DYNAMICS (EURODYN 2017); v. 59, p. 10-pg., 2013-01-01.

Abstract

Osteoporosis is defined by the National Institutes of Health as a skeletal disorder characterized by compromised bone strength, increasing fracture risk. Samples of vertebral cancellous bone were extracted from human cadavers from the T12 region. The comparative pre-selection of bone into the three groups was performed using the calcaneal ultrasonometry and evaluated by image analysis: microtomography, X-ray diffraction, optical microscopy e scanning electron microscopy. The results showed, for the diseased bone, degradation, reduction in the histomorfometric parameters and lower X-ray intensity. It is concluded that this characteristics indicates a validation in the assessment of fracture risk. (C) 2013 The Authors. Published by Elsevier Ltd. (AU)