| Full text | |
| Author(s): |
de Araujo Lima, Tais Figueiredo
;
Costa da Silva Behrens, Nilce Sanny
;
Lopes, Eduardo
;
Pereira, Danielle
;
Fonseca, Hassana de Almeida
;
Cavalcanti, Paola Oliveira
;
Pradella-Hallinan, Marcia
;
Castro, Juliana
;
Tufik, Sergio
;
Santos Coelho, Fernando Morgadinho
Total Authors: 10
|
| Document type: | Journal article |
| Source: | SLEEP SCIENCE; v. 7, n. 2, p. 4-pg., 2014-06-01. |
| Abstract | |
The Kleine-Levin Syndrome is a differential diagnosis for patients with diurnal excessive sleepiness and a suspicion of narcolepsy. It is characterized by paroxysmal attacks of diurnal excessive sleepiness, associated with one or more symptoms of hyperphagia, hypersexuality, coprolalia and copropraxia. During crisis intervals, there are no symptoms. This pathology predominantly manifests itself in teenagers, being more frequent among males. The course of this disease is unpredictable, with variable duration and frequency. The most accepted physiopathology is that of a hypothalamic dysfunction, although and recently, there has appeared a hypothesis of a post-infectious autoimmune disorder. These patients show an elevated body mass index, which can predispose to association with comorbidities such as the sleep obstructive apnea syndrome. Treatment involves medications with different effects, but there is no specific and effective therapy. Our article shows a classic case of Kleine-Levin Syndrome associated with sleep obstructive apnea syndrome, a rare association in the literature. (C) 2014 Brazilian Association of Sleep. Production and Hosting by Elsevier B.V. (AU) | |
| FAPESP's process: | 98/14303-3 - Center for Sleep Studies |
| Grantee: | Sergio Tufik |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |