Complete Genome Sequence of an Atypical Dengue Virus Serotype 2 Lineage Isolated in Brazil

Author(s)

Salvador, Felipe Scassi ; Amorim, Jaime Henrique ; Santos Alves, Rubens Prince ; Pereira, Sara A. ; Souza Ferreira, Luis Carlos ; Romano, Camila Malta

• Document type: Journal article
• Source: GENOME ANNOUNCEMENTS; v. 3, n. 4, p. 2-pg., 2015-07-01.

Abstract

Here, we report the complete polyprotein sequence of a dengue virus 2 strain isolated in Brazil. This virus belongs to the American genotype and has the ability to cause neurovirulence in immunocompetent adult mice. The data presented here may help understand the genetic determinants responsible for neurovirulence. (AU)

• FAPESP's process: 12/15381-7 - Characterization of adaptive mutations in dengue virus serotype 2 (DENV2) cultured in different systems using high-throughput sequencing
• Grantee: Camila Malta Romano
• Support Opportunities: Regular Research Grants
• FAPESP's process: 12/51204-2 - A new way for the rational pursuit of an effective vaccine against dengue
• Grantee: Jaime Henrique Amorim Santos
• Support Opportunities: Scholarships in Brazil - Post-Doctoral